اخبار و اعلانات

دانشگاه سیستان و بلوچستان

آمار

تعداد نشریات25
تعداد شماره‌ها423
تعداد مقالات4,312
تعداد مشاهده مقاله6,544,121
تعداد دریافت فایل اصل مقاله4,340,200
Ebrahim, Shiva Ebrahim, Motamedi, Masoumeh, Mehrabi, Fatemeh. (1398). Analysis of Cell-Free DNA in an Iranian Women Undergoing IVF. نشریه علمی دانشگاه سیستان و بلوچستان, (), -. doi: 10.22111/jep.2019.5031
Shiva Ebrahim Ebrahim; Masoumeh Motamedi; Fatemeh Mehrabi. "Analysis of Cell-Free DNA in an Iranian Women Undergoing IVF". نشریه علمی دانشگاه سیستان و بلوچستان, , , 1398, -. doi: 10.22111/jep.2019.5031
Ebrahim, Shiva Ebrahim, Motamedi, Masoumeh, Mehrabi, Fatemeh. (1398). 'Analysis of Cell-Free DNA in an Iranian Women Undergoing IVF', نشریه علمی دانشگاه سیستان و بلوچستان, (), pp. -. doi: 10.22111/jep.2019.5031
Ebrahim, Shiva Ebrahim, Motamedi, Masoumeh, Mehrabi, Fatemeh. Analysis of Cell-Free DNA in an Iranian Women Undergoing IVF. نشریه علمی دانشگاه سیستان و بلوچستان, 1398; (): -. doi: 10.22111/jep.2019.5031

Analysis of Cell-Free DNA in an Iranian Women Undergoing IVF

Journal of Epigenetics
مقالات آماده انتشار، پذیرفته شده، انتشار آنلاین از تاریخ 02 آذر 1398  XML
نوع مقاله: Original Article
شناسه دیجیتال (DOI): 10.22111/jep.2019.5031
نویسندگان
Shiva Ebrahim Ebrahim1؛ Masoumeh Motamedi email 2؛ Fatemeh Mehrabi3
1Department of Biology, central Tehran branch, Islamic Azad University, Tehran, Iran
2Kowsar Human Genetics Research Institute, Yas medical Genetics Lab, Tehran, Iran
3Infertility center of Tehran Yas hospital, medical school of Tehran University of medical science, Tehran, Iran
چکیده
1) Background: One of the treatments offered to women with infertility is IVF (In vitro fertilization). The Cell free DNA in plasma/follicles were suggested as a biomarker for embryo quality in IVF. Higher the levels of Cell-free DNA indicate poorer embryo quality in the follicular fluid during IVF. Therefore this study was designed to examine the cell-free DNA (cfDNA) in plasma and Fluid-follicle of women undergoing IVF-embryo transfer. 2) Methods: The study examined 100 women undergoing IVF treatment in an IVF unit in Yas Hospital of Tehran University of Medical Sciences in Tehran-Iran. Cell-free DNA was extracted from plasma and follicular fluid of patients using the NucleoSpin® Extraction Kit. The total cfDNA was examined by qPCR for ALBUMIN and GAPDH genes. 3) Results: we did not find significant association between the variables including CT-plasma, CT-follicular fluid, delta-CT and average of these data between two studied groups (patients with successful and unsuccessful IVF). 4) Conclusion: Plasma and follicular fluid cfDNA may reflect the presence of factors which interfere with embryo implantation. Further research is required to determine the usefulness of cfDNA as a biomarker of IVF outcome and to examine the underlying pathologies as potential sources for increased plasma/follicular fluid cfDNA concentrations.
کلیدواژه‌ها
Follicular fluid؛ plasma؛ IVF؛ ALBUMIN؛ GAPDH
آمار
تعداد مشاهده مقاله: 5


Contact Us | Help & Support | Site Map

Journal Management System. Designed by sinaweb.